Cart
sales@molnova.com
Delavirdine mesylate
CAS No. 147221-93-0
Delavirdine mesylate ( U 90152 )
Catalog No. M12020 CAS No. 147221-93-0
A potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 49 | In Stock |
|
| 50MG | 68 | In Stock |
|
| 100MG | 78 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDelavirdine mesylate
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT.
-
DescriptionA potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT; exhibits IC50>440 uM for DNA polymerases α and δ; blocks the replication in peripheral blood lymphocytes of 25 primary HIV-1 isolates and has low cellular cytotoxicity; retains significant activity against mutant RTs (K103N, Y181C).HIV Infection Approved
-
SynonymsU 90152
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV
-
Research AreaInfection
-
IndicationHIV Infection
Chemical Information
-
CAS Number147221-93-0
-
Formula Weight552.67
-
Molecular FormulaC23H32N6O6S2
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 40.3 mg/mL
-
SMILESO=C(N1CCN(C2=NC=CC=C2NC(C)C)CC1)C(N3)=CC4=C3C=CC(NS(=O)(C)=O)=C4.CS(=O)(O)=O
-
Chemical NameMethanesulfonamide, N-[2-[[4-[3-[(1-methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]-, methanesulfonate (1:1)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Dueweke TJ, et al. Antimicrob Agents Chemother. 1993 May;37(5):1127-31.
2. Romero DL, et al. J Med Chem. 1993 May 14;36(10):1505-8.
3. Olmsted RA, et al. J Virol. 1996 Jun;70(6):3698-705.
2. Romero DL, et al. J Med Chem. 1993 May 14;36(10):1505-8.
3. Olmsted RA, et al. J Virol. 1996 Jun;70(6):3698-705.
molnova catalog
related products
-
DMJ-I-228
A small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
-
Fostemsavir Tris
Fostemsavir Tris is the prodrug of BMS-626529,is a oral, safe and effective?inhibitor of HIV-1 attachment.?It inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells.
-
4-Chloro-2-(trifluor...
4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) .
